MLB Game Preview: St. Louis Cardinals (12-8) vs. Houston Astros (8-14)

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Houston Astros logo

First Pitch: 11:10 AM PT / 1:10 PM CT

Venue: Daikin Park — Houston, TX

Weather: Indoor ballpark (roofed), so weather will not affect gameplay.

Team Records & Statistical Profile

St. Louis Cardinals (12–8)

Record entering game: 12–8 (per ESPN game listing)

Runs Scored: 80

Team AVG: .231

OBP: .326

SLG: .369

HR: 20

Runs/Game: 4.4 (14th MLB)

Pitching:

ERA: 4.94

WHIP: 1.45

HR Allowed: 18

Strikeouts: 111

Walks: 71

FIP: 4.72

Bullpen:

6 saves in 8 chances (75%)

15 holds (7th MLB)

36.4% inherited runners scored

Houston Astros (8–14)

Record entering game: 8–14 (per ESPN game listing)

Recent Offensive Highlight: Yordan Alvarez HR and RBI in previous matchup vs STL

Team Offense (from box score context):

3 hits in previous game

1 HR (Alvarez)

0–6 with RISP

Recent Team Form

Cardinals — Last 5

W, W, W, W, L (4–1 stretch)

Astros — Last 5

L, L, L, W, W (2–3 stretch)

Series History & Context

Cardinals won the most recent matchup 7–2, powered by HRs from Burleson, Winn, and Fermín.

Astros struggled offensively in that game, going 0–6 with runners in scoring position.

Probable Pitching Matchup

STL — Matthew Liberatore (LHP)

Cardinals’ pitching staff overall:

ERA: 4.94

WHIP: 1.45

K/BB ratio: 1.56

HOU — Mike Burrows (RHP)

Astros’ pitching context from box score:

McCullers Jr. allowed 4 ER in 5 IP

Bullpen allowed 3 additional ER

Key Player Matchups

St. Louis Cardinals

Alec Burleson: HR + 2 hits in previous game

Masyn Winn: HR + 2 RBI

Nick Gorman: 2 RBI

J. Wetherholt: Reached base twice

Houston Astros

Yordan Alvarez: HR, 2 hits, 1 RBI

Jose Altuve: Reached base twice

Taylor Trammell: Stolen base

Betting Trends

Cardinals bullpen: 75% save rate, strong leverage performance.

Cardinals offense: 20 HR, solid OBP (.326).

Astros offense: Struggling recently (3 hits in last game).

Astros RISP issues: 0–6 in previous matchup.

Game Odds

St. Louis Cardinals           8.5

Houston Astros                 – 149

Odds Courtesy of Sports Odds Direct as of Saturday, April 18, 2026