MLB Game Preview: Arizona Diamondbacks (9-8) vs. Baltimore Orioles (9-7)

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Baltimore Orioles logo

Oriole Park at Camden Yards, Baltimore, MD
First pitch is scheduled for 6:35 PM EDT
TV: MASN, Dbacks.TV, MLB.TV

This early-season interleague matchup pits a streaking Orioles club riding a three-game win streak (including a 9-7 victory over these same Diamondbacks on Monday) against a Diamondbacks squad looking to bounce back from that loss and stabilize after a slow start to the year. Baltimore sits atop the AL East with a +3 run differential; Arizona is third in the NL West and even on run differential. Both teams are scoring around 4.0 runs per game early on.

Team Records & Recent Form

Diamondbacks (9-8, 3rd NL West): Arizona got off to a 9-5 stretch after dropping its first three games but has cooled slightly. They are 4-6 on the road and 6-4 in their last 10 overall. Offense has been powered by contact and speed, but the bullpen has been taxed in high-scoring games (16 combined runs allowed in Monday’s bullpen-heavy affair). They average 4.00 runs scored and allow roughly 4.00.

Orioles (9-7, 1st AL East): Baltimore has won three straight and six of its last 10, showing strong home form (6-4). The lineup features power and on-base ability, ranking near the top in extra-base hits early. They score 4.00 runs per game while allowing 4.07 but have momentum and home-field advantage in this series.

Weather Updates

Warm and hitter-friendly conditions at Camden Yards: temperatures around 85–86°F with low humidity (~29%), winds 12–13 mph blowing out (favorable for fly balls, especially to left/center). Precipitation probability is only ~10%. Expect a fast-paced, high-scoring affair with minimal weather impact—clear skies and ideal April evening baseball.

Injury Report

Arizona Diamondbacks

Merrill Kelly (RHP): Activated from 15-day IL (intercostal/back); making season debut tonight.

Gabriel Moreno (C): 10-day IL (back).

Pavin Smith (1B): 10-day IL.

Carlos Santana (1B): 10-day IL.

Tyler Locklear (INF): 10-day IL (elbow).

Corbin Carroll (RF): Day-to-day (minor, expected to play).

Depth at catcher and first base is tested; Kelly’s return is a boost but his rust is a factor.

Baltimore Orioles

Ryan Mountcastle (1B/DH): Foot fracture; on IL (recently moved to 60-day in some reports).

Jackson Holliday (INF): 10-day IL (finger).

Heston Kjerstad (OF): 10-day IL (hamstring).

Baltimore is without key power and middle-infield depth but still fields a dangerous lineup with Gunnar Henderson, Adley Rutschman, and others producing.

Key

Player Matchups to Watch / Probable Pitchers

Merrill Kelly (ARI, RHP, 0-0, season debut) vs. Trevor Rogers (BAL, LHP, 2-0, 1.89 ERA)
Kelly returns after missing the start of the year and will be on a limited pitch count. He was solid in 2025 (12-9, 3.52 ERA) but faces a hot Orioles lineup that feasts on righties. Rogers has been dominant early (19 IP, 14 K, 1.05 WHIP) and provides length—key against Arizona’s aggressive bats.

Corbin Carroll (.343, multi-extra-base hits lately) vs. Rogers’ changeup: Carroll’s speed and contact could exploit any early-command issues.

Gunnar Henderson (power surge) & Orioles middle order vs. Kelly’s fastball: Expect heavy pull-side damage if Kelly leaves pitches up.

Bullpens: Both relieved heavily Monday; Arizona’s pen has been vulnerable lately. Special teams equivalent (baserunning/defense) favors Baltimore at home.

Series History

This is Game 2 of a three-game set. Baltimore took Game 1 (9-7) on Monday with late offense. All-time interleague play is relatively even (D-backs lead slightly historically), but the 2026 season series now favors the Orioles 1-0 after yesterday’s high-scoring affair. Arizona is 3-6 in its last nine against Baltimore.

Betting Trends

Orioles are 5-1 as -130 or better favorites this year and strong at home.

Total has gone Over in 4 of Arizona’s last 6 games.

Diamondbacks are 6-3 straight-up in last 9 but 3-6 vs. Baltimore.

Rogers’ hot start gives Baltimore the pitching edge; Kelly’s rust points to middle-inning scoring.

Game Odds

Arizona Diamondbacks                 8.5

Baltimore Orioles                            – 149

Odds Courtesy of Sports Odds Direct as of Monday, April 13, 2026