First pitch is scheduled for 7:15 p.m. ET
Coverage: FOX / MLB.TV / Cardinals.TV
Game Context & Team Records
The Red Sox arrive in St. Louis at 4-9 (5th in the AL East, 1-6 on the road) after dropping the series opener 3-2 on Friday night in a tightly contested affair. Boston has struggled mightily away from Fenway, posting a dismal road record early while their offense has been inconsistent (around 3.60 runs/game). The Cardinals sit at 8-5 (2nd/3rd in the NL Central, 5-2 at home) and have won three straight at Busch Stadium, including Friday’s walk-off style victory. St. Louis is playing solid home baseball and looking to push their winning streak to four while even further distancing themselves in the early NL Central race.
Weather Update
Game-time conditions at Busch Stadium will be mild and mostly favorable for baseball:
Temperature: ~73°F (dropping into the upper 60s by late innings)
Winds: 8 mph (light, out to center or variable)
Humidity: ~59%
Precip probability: ~21% (isolated showers possible but low impact expected)
Expect comfortable evening conditions with neutral-to-slightly hitter-friendly wind early; the roof stays open. No major weather concerns for scoring or play.
Injury Report
Boston Red Sox (key absences):
SP Patrick Sandoval (15-day IL – elbow recovery)
SP Kutter Crawford (15-day IL)
SP Tanner Houck (60-day IL – elbow)
1B Triston Casas (10-day IL – knee)
RP Justin Slaten (15-day IL – oblique)
INF Romy Gonzalez (60-day IL – shoulder)
St. Louis Cardinals (key absences):
SS Masyn Winn (day-to-day – knee, exited Friday after HBP; status uncertain for Saturday)
SP Hunter Dobbins (15-day IL – knee)
RP Matt Pushard (15-day IL – knee)
OF Lars Nootbaar (60-day IL – heels)
Boston’s rotation and lineup depth are hit hard, while St. Louis is mostly healthy aside from the shortstop question mark.
Probable Pitchers & Key Player Matchups
Red Sox: LHP Ranger Suarez (0-1, 8.64 ERA, 1.92 WHIP, 8.1 IP)
Suarez has been hit hard early (13 H, 2 HR allowed). He’ll face a Cardinals lineup featuring:
Nolan Gorman (power threat vs lefties).
Alec Burleson (consistent contact hitter).
Speed/defense from players like Tommy Edman or Brendan Donovan if Winn sits.
Cardinals: RHP Kyle Leahy (1-1, 5.40 ERA, 1.80 WHIP, 10.0 IP)
Leahy has shown flashes but surrendered 13 hits and 5 walks in limited work. He’ll duel a Red Sox lineup paced by:
Rafael Devers (elite bat, dangerous vs righties).
Jarren Duran (speed and extra-base pop).
Emerging young talent like Marcelo Mayer or Ceddanne Rafaela providing contact.
Edge: Both starters have elevated early ERAs, setting up a potential offensive showcase rather than a duel. Leahy’s home splits give St. Louis a slight pitching nod.
Recent Team Forms
Red Sox (4-9, L1): Split a series with Milwaukee (won the final two) before Friday’s narrow loss. Road woes persist (1-6), and the bullpen has been overworked. Offense has shown occasional pop but lacks consistency.
Cardinals (8-5, W1): Strong 5-2 home start and winners of three straight overall. They took the series opener vs Boston and closed out Washington convincingly. Balanced attack with good bullpen usage lately.
Series History
2026 Season: Cardinals lead this series 1-0 after Friday’s 3-2 win.
Recent Seasons: Mixed—Boston swept St. Louis 3-0 in 2025; Cardinals took 2 of 3 in 2024.
All-Time: Nearly even (Red Sox ~14-15 vs Cardinals). Interleague play at Busch has been competitive, but the home team has the recent edge.
Betting Trends
Red Sox are slight road favorites on paper due to reputation, but their 1-6 away mark and Suarez’s poor start make this shaky. Cardinals are 5-2 home and have covered in recent home wins. Pitching mediocrity + mild weather leans toward the over, but early-season bullpen fatigue could suppress scoring.
Game Odds
Boston Red Sox – 143
St. Louis Cardinals 8
Odds Courtesy of Sports Odds Direct as of Friday, April 10, 2026
